cost effective experimental design and execution of functional genomics projects based on the RIBO-seq platform.
TB-Seq specializes in application and development of experimental and computational procedures for translatome analysis (ribosome profiling) of mammalian cell lines and tissues, plants, fungi, bacterial cultures, and metagenome communities.
Let’s work on your project together
Since 2015, TB-Seq has provided to its international customers from academia, biotech and pharma the highest quality experimental and computational products in ribosome profiling (RIBO-seq) analysis. We offer competitive pricing, fast turn-around, highest quality of execution, and customized project and experimental design and execution, to fit your needs from data collection, through data analysis, to result summary.
TB-Seq Inc. labs are located in South San Francisco CA, at the core of the San Francisco peninsula Biotech hub and in close proximity to Stanford University and UCSF.
We will be glad to discuss with you your project details.
RIBO-seq library preparation
We are experienced in isolating ribosome-bound mRNA from bacterial and eukaryotic cells, and from animal and plant tissues. We have developed sample-specific efficient protocols for all steps of the RIBO-seq procedure, from lysis to library preparation, that allow us to create RIBO-seq libraries of the highest quality from the smallest amount of starting material.
Our proprietary optimized RIBO-seq protocols allow us to produce RIBO-seq libraries of the highest quality more efficiently and with enhanced sensitivity compared to competing protocols.
We will be glad to prepare RNA-seq libraries in parallel to RIBO-seq libraries upon request. Comparing RNA-seq to RIBO-seq data allows to measure “translation efficiency”, i.e., rate of translation per mRNA unit.
We have partnered with sequencing facilities that guarantee fast sequencing services on Illumina HiSeq or NovaSeq sequencers.
Bioinformatics analysis of NGS data
TB-Seq offers a wide range of bioinformatics analyses based on RIBO-seq and RNA-seq sequencing data.
Besides quality-control, gene expression and differential expression analyses, we perform customized analyses tailored to your research needs, using available software packages, our suite of bioinformatics tools, or developing ad hoc analytical tools.
Our team works side-by-side with each client to understand their research questions and to ensure alignment in the study objectives.
All information on our ribosome profiling services is subject to change without notice. Please contact TB-SEQ Inc. for latest pricing and terms.